Memory depends on coordination between local processing, indexed by high-frequency broadband (HFB) activity, and global network organization, indexed by theta rhythms. We used direct brain recordings from key regions supporting memory to understand how the results of local processing are communicated through the network. By anchoring analyses of theta phase clustering and connectivity to HFB peaks on a trial-by-trial basis, we discovered how transient brain states linked to internal physiological events support memory. Graph analysis further revealed specific connections amid sparse network connectivity during memory success, challenging the party line that ‘more connectivity is better’. Paper published in PLoS Biology.
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