Working memory enables us to keep sequences of information in mind. Using direct brain recordings from the hippocampus, orbitofrontal cortex, and amygdala, we reveal that slow and fast theta rhythms have opposing effects on working memory performance. Slow theta synchrony between the hippocampus and orbitofrontal cortex improved performance, while fast theta synchrony between the same regions impaired it. Our results establish that working memory success depends not only on which brain regions can interact, but at what frequency. Check out the preprint!
dynamic brain lab 